Key result
Electric cardioversion of persistent atrial fibrillation significantly decreased lateral e' (from 12.8 to 9.8 cm/s, P<0.001) and septal e' (from 9.5 to 7.1 cm/s, P<0.001) at 1 month.
Why the study?
Does restoration of sinus rhythm by electric cardioversion change early diastolic mitral annular velocity (e') in patients with persistent atrial fibrillation?
Observational (n=30)
Does restoration of sinus rhythm by electric cardioversion change early diastolic mitral annular velocity (e') in patients with persistent atrial fibrillation?
Absolute Event Rate: 9.8% vs 12.8%
p-value: p=<0.001
Early diastolic mitral annular velocity (e') is significantly higher during atrial fibrillation than during sinus rhythm, suggesting that diastolic dysfunction may be masked by seemingly normal e' values in AF patients.
AIMS: The early diastolic mitral annular velocity (e') and mitral E/e' criteria for clinically evaluating diastolic dysfunction in patients with atrial fibrillation (AF) are almost the same as in patients with sinus rhythm. In this study, we aimed to investigate whether e' is useful to assess diastolic function in AF patients. METHODS: Thirty patients who underwent successful electric cardioversion (EC) due to persistent AF and who maintained sinus rhythm for 1 month after EC were enrolled in this study. Transthoracic echocardiography was performed on all patients before and 1 month after EC. Standard diastolic parameters, the global longitudinal strain (GLS), and left ventricular (LV) twist were measured. RESULTS: Conventional Doppler parameters measured before EC were not significantly different from 1 month after EC. However, the lateral and septal e' were significantly decreased 1 month after EC (from 12.8 ± 2.5 to 9.8 ± 2.3 cm/s and from 9.5 ± 1.9 to 7.1 ± 1.5 cm/s, respectively, P < 0.001). Likewise, the lateral and septal E/e' were also significantly increased 1 month after EC (P < 0.001). The GLS was significantly improved from -15.9 ± 2.2% to -19.4 ± 2.4% after EC (P < 0.001), as was the LV twist (from 5.8 ± 1.7° to 9.1 ± 2.4°, P < 0.001). CONCLUSION: We demonstrated that e' was significantly higher in AF compared with during sinus rhythm in the same patients. Thus, in AF patients, diastolic dysfunction should be suspected even when e' values are normal.
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Park et al. (2018) conducted an observational in persistent atrial fibrillation (n=30). Electric cardioversion vs. Baseline (before cardioversion) was evaluated on lateral early diastolic mitral annular velocity (e') (p=<0.001). Electric cardioversion of persistent atrial fibrillation significantly decreased lateral e' (from 12.8 to 9.8 cm/s, P<0.001) and septal e' (from 9.5 to 7.1 cm/s, P<0.001) at 1 month.
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