August 20, 2013European Journal of Preventive Cardiology
Follow-up of ischaemic heart disease in patients with coeliac disease
Key result
Coeliac disease in patients with myocardial infarction was associated with significantly higher one-year all-cause mortality compared to controls without coeliac disease (OR 1.43; 95% CI 1.04-1.95).
Why the study?
Does coeliac disease affect one-year mortality and treatment outcomes in patients with myocardial infarction?
Population
2,418 Swedish patients with myocardial infarction from the SWEDEHEART register, including 430 patients with…
Comparison
Coeliac disease (exposure) vs General population controls with myocardial…
Design
Cohort
Follow-up
one year
Authors
Discussion
Loading...
Member takes
Implication
May prompt closer post-MI monitoring in coeliac disease; leaves open causal mechanisms and intervention trials.
Study Design
Type
Cohort (n=2,418)
Multicenter
Yes
Structured PICO
Does coeliac disease affect one-year mortality and treatment outcomes in patients with myocardial infarction?
P
Population
2,418 Swedish patients with myocardial infarction (MI) from the SWEDEHEART register (2005-2008), including 430 patients with coeliac disease (villous atrophy; Marsh histopathology stage 3 based on biopsy) and 1,988 general population controls with MI.
I
Intervention
Coeliac disease (exposure)
C
Comparator
General population controls with myocardial infarction without coeliac disease
O
Outcome
One-year all-cause mortality and percutaneous coronary intervention (PCI) rateshard clinical
Main Result
Effect estimate: OR 1.43 (95% CI 1.04-1.95)
Patients with coeliac disease and myocardial infarction have higher one-year mortality and lower rates of PCI compared to controls, despite similar follow-up clinical parameters.
Cite This Study
Emilsson et al. (2013) conducted a cohort in Myocardial infarction and coeliac disease (n=2,418). Coeliac disease vs. Controls without coeliac disease was evaluated on One-year all-cause mortality (OR 1.43, 95% CI 1.04-1.95). Coeliac disease in patients with myocardial infarction was associated with significantly higher one-year all-cause mortality compared to controls without coeliac disease (OR 1.43; 95% CI 1.04-1.95).