Population
Patients with disseminated intravascular coagulation (DIC)
Design
Cohort
Authors
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Protein C depletion may contribute to DIC progression; supports regulatory role but leaves open whether supplementation improves outcomes.
Protein C activity and its inhibitor decrease progressively during the initial stages of DIC, suggesting a major role for protein C in the control of the condition.
Marlar et al. (1985) studied this question.
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