What does this research mean for the field?

A local tissue renin-angiotensin system exists, most prominently in the kidney, where it utilizes circulating renin to locally synthesize angiotensins for the long-term regulation of renal vascular resistance and blood pressure. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

April 1, 1997The Annual Review of Pharmacology and Toxicology

TISSUE RENIN-ANGIOTENSIN SYSTEM:A Site of Drug Action?

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Design

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Authors

BABen G. Zimmerman andUniversity of Minnesota EDEarl W. DunhamUniversity of Minnesota

Discussion

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Implication

Supports renal RAS role in hypertension pathophysiology; leaves open whether tissue-specific targeting improves outcomes beyond systemic blockade.

Key Points

Key points are not available for this paper at this time.

Cite This Study

and et al. (1997) studied this question.

synapsesocial.com/papers/6a1a1cf6443d3ecd7cdf5cf4 https://doi.org/10.1146/annurev.pharmtox.37.1.53

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Implication

Supports renal RAS role in hypertension pathophysiology; leaves open whether tissue-specific targeting improves outcomes beyond systemic blockade.

TISSUE RENIN-ANGIOTENSIN SYSTEM:A Site of Drug Action?

Discussion

Member takes

Implication

Key Points

Cite This Study

TISSUE RENIN-ANGIOTENSIN SYSTEM:A Site of Drug Action?

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider