Why the study?
The authors sought to evaluate changes in ventricular repolarization parameters on preoperative and postoperative ECGs of patients undergoing mitral valve repair for mitral valve prolapse.
Does surgical mitral valve repair improve ventricular repolarization parameters in patients with mitral valve prolapse and severe mitral regurgitation?
Does surgical mitral valve repair improve ventricular repolarization parameters in patients with mitral valve prolapse and severe mitral regurgitation?
Surgical mitral valve repair in patients with mitral valve prolapse significantly shortens ventricular repolarization parameters, which may theoretically reduce the risk of ventricular arrhythmias and sudden cardiac death.
May support arrhythmia risk reduction post-repair; hypothesis-generating, requires prospective validation before practice change.
Objective: To evaluate the changes in ventricular repolarization parameters in preoperative and postoperative electrocardiograms (ECGs) of patients who underwent mitral valve repair (MVR) for mitral valve prolapse.Methods: Patients who underwent MVR due to mitral valve prolapse with severe mitral regurgitation were included in the study.A resting 12-lead ECG was recorded both preoperatively and 6 months postoperatively.QT, QTc, cQTd, JT, JTc, and Tp-e were measured; Tp-e/QT and Tp-e/QTc ratios were calculated. Results:The study included 53 patients (58.5% male), with a mean age of 52.713 years.The durations of PR, QRS, QT, cQT, cQTd, JT, cJT, and Tp-e were reduced significantly (P<0.001) six months after repair. Conclusions:The repolarization parameters changed after MVR surgery.Shortening of the QT, cQT, cQTd, JT, cJT, and Tp-e durations after the repair procedure may reduce the risk of sudden cardiac death, and arrhythmias in MVP.
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Savur et al. (2025) studied this question.
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