What question did this study set out to answer?

March 26, 2008Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy

Comparison of Drug Adherence Rates Among Patients with Seven Different Medical Conditions

View Full Paper

Ask AI

Bookmark

Why the study?

How do drug adherence rates compare among patients initiating therapy for seven different chronic medical conditions?

Population

706,032 adults aged 18 years or older with at least one of seven medical conditions and with incident use of…

Design

Cohort

Follow-up

1 year

Authors

BBBecky A. BriesacherNortheastern University SASusan E. AndradeHarvard University HFHassan FouayziUniversity of Massachusetts Chan Medical School

Discussion

Member takes

Implication

Adherence appears highest for hypertension initiation; extends comparative adherence data but leaves open condition-specific barriers and intervention targets.

Key Points

The study aims to compare drug adherence rates among patients with seven different medical conditions using a standardized method.
Longitudinal study analyzing health care claims data from 2001-2004 with 706,032 adults.
Measured drug adherence as total days' supply over the first year and accounted for covariates like age and comorbidity.
Utilized bivariate statistics and stratification analyses to assess adherence across different conditions.
72.3% of individuals with hypertension achieved adherence rates of 80% or better, while adherence rates for other conditions were lower.
Adherence decreased with increased comorbidity for osteoporosis, but increased for hypertension, hypercholesterolemia, and gout.
Previous experience with drug therapy improved adherence in hypertension, type 2 diabetes, hypothyroidism, or seizure disorders.

Structured PICO

How do drug adherence rates compare among patients initiating therapy for seven different chronic medical conditions?

Population

706,032 adults aged 18 years or older with at least one of seven medical conditions (gout, hypercholesterolemia, hypertension, hypothyroidism, osteoporosis, seizure disorders, and type 2 diabetes mellitus) and with incident use of drug therapy for that condition.

Intervention

Incident use of drug therapy for the respective medical condition

Outcome

Drug adherence measured as the sum of the days' supply of drug therapy over the first year observed

Drug adherence varies significantly by medical condition, with hypertension having the highest adherence (72.3% achieving ≥80% adherence) and gout the lowest (36.8%).

Cite This Study

Briesacher et al. (2008) studied this question.

synapsesocial.com/papers/6a1a5c99ca4263d615b87723 https://doi.org/10.1592/phco.28.4.437

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Implication

Adherence appears highest for hypertension initiation; extends comparative adherence data but leaves open condition-specific barriers and intervention targets.

Comparison of Drug Adherence Rates Among Patients with Seven Different Medical Conditions

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Comparison of Drug Adherence Rates Among Patients with Seven Different Medical Conditions

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider