Why the study?
Can systolic time intervals serve as a non-invasive aid to evaluate left ventricular function in patients with aortic insufficiency?
Can systolic time intervals serve as a non-invasive aid to evaluate left ventricular function in patients with aortic insufficiency?
Left ventricular ejection time correlates inversely with ejection fraction and mean shortening velocity, suggesting its utility as a non-invasive marker of LV function in aortic insufficiency.
May support corrected ejection time as non-invasive LV function marker in aortic insufficiency; hypothesis-generating, requires prospective validation.
In fourteen patients with aortic insufficiency, the interrelations among the systolic time intervals and other hemodynamic measurements were studied by means of cardiac catheterization and angiocardiography. The pre-ejection period was within the normal range in nine patients. The left ventricular ejection time and the total electromechanical systole were prolonged above normal in almost all the patients. The left ventricular ejection time corrected for heart rate exhibited a close inverse relationship to both the ejection fraction and the mean shortening velocity per unit length of the myocardium. These findings suggest that the left ventricular ejection time can be a non-invasive aid of clinical use in evaluating the left ventricular function in patients with aoric insufficiency.
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Watanabe et al. (1971) studied this question.
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