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February 1, 2019Minerva Medica

Epidemiological studies show a strong association between obesity and AF, with a 4-5% increase in AF risk for every unit increase in BMI.

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Why the study?

Prevalence of obesity, MetS, and T2D is escalating and markedly increases the risk of developing AF and stroke through deleterious effects on the heart.

Population

Patients with cardiometabolic disturbances including obesity, MetS, and T2D

Design

Review

Authors

FSFrancesco De SensiUniversity of Rome Tor VergataSCSarah CostantinoHeart Failure & TransplantULUgo LimbrunoInterventional Cardiology

Discussion

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Overview

May support obesity counseling in AF prevention; confirms association but leaves open intervention effects.

Structured PICO

P
Population
Patients with cardiometabolic disturbances including obesity, metabolic syndrome (MetS), and type 2 diabetes (T2D) at risk for or with atrial fibrillation (AF)

This review highlights the strong association between cardiometabolic conditions and atrial fibrillation, emphasizing the need for targeted therapeutic strategies including weight loss and lifestyle changes.

Cite This Study

Sensi et al. (2019) studied this question.

synapsesocial.com/papers/6a1a71bc7ff99bba0645ae76https://doi.org/10.23736/s0026-4806.18.05882-2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Obesity and Atrial Fibrillation: Epidemiology, Mechanisms, and Therapeutic Implications in the Era of Metabolic Therapies2026 · 1 citations
  2. 2Obesity, Diabetes and Atrial Fibrillation; Epidemiology, Mechanisms and Interventions2012 · 93 citations
  3. 3Atrial fibrillation and metabolic syndrome: an updated review of mechanisms, risk factors, and therapeutic strategies2026
  4. 4Diabetes, Obesity and Atrial Fibrillation: Epidemiology, Mechanisms and Interventions.2013 · 9 citations
  5. 5Obesity and Atrial Fibrillation: From Mechanisms to Treatment2025 · 12 citations