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May 19, 2026Frontiers in Cardiovascular MedicineOpen Access

Metabolic syndrome confers a 1.5- to 2-fold increased risk of developing atrial fibrillation compared with the general population.

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Why the study?

The association between metabolic syndrome and atrial fibrillation remains incompletely understood, with ongoing debates regarding the independent contributions and synergistic interactions of individual metabolic components in modifying the atrial substrate.

Design

Review

Key result

Metabolic syndrome confers a 1.5- to 2-fold increased risk of developing atrial fibrillation compared with the general population.

Discussion

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Overview

MetS screening may refine AF risk assessment now; leaves open component-specific interventions for prevention.

Structured PICO

P
Population
Patients with metabolic syndrome and atrial fibrillation

Main Result

Effect estimate: 1.5-2 times increased risk

This review highlights the multifactorial mechanisms linking metabolic syndrome to a 1.5-2 fold increased risk of atrial fibrillation, emphasizing the need for early preventive approaches.

Cite This Study

A 2026 study conducted a review in Atrial fibrillation and metabolic syndrome. Metabolic syndrome vs. General population was evaluated on Atrial fibrillation development (1.5-2 times increased risk). Metabolic syndrome confers a 1.5- to 2-fold increased risk of developing atrial fibrillation compared with the general population.

synapsesocial.com/papers/6a7ca397ec6509d062ba5c9chttps://doi.org/10.3389/fcvm.2026.1666063
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Atrial Fibrillation and Metabolic Syndrome: Understanding the Connection.2012 · 20 citations
  2. 2What Do We Currently Know About Metabolic Syndrome and Atrial Fibrillation?2013 · 36 citations
  3. 3The Role of Different Components of Metabolic Syndrome in the Pathogenesis of Atrial Fibrillation2024 · 2 citations
  4. 4Cardiometabolic Risk Factors and Atrial Fibrillation2013 · 27 citations
  5. 5Atrial fibrillation in the cardiometabolic patient2019 · 39 citations