Why the study?
Does the presence of hypertension correlate with the risk of early death in patients with spontaneous subarachnoid hemorrhage?
Does the presence of hypertension correlate with the risk of early death in patients with spontaneous subarachnoid hemorrhage?
Hypertension is highly prevalent in patients with spontaneous subarachnoid hemorrhage and is significantly associated with an increased risk of early death within 14 days.
Hypertension may signal higher early mortality risk after spontaneous subarachnoid hemorrhage; leaves open whether blood pressure control improves outcomes.
One hundred and eighteen consecutive cases of spontaneous subarachnoid haemorrhage seen at one hospital during a three-year period were examined to assess the prevalence of hypertension and the correlation between the presence of hypertension and the risk of early death. Eighty-seven of the patients had intracranial aneurysms. The diagnosis of hypertension was determined by means of three complementary criteria: a history of treatment with antihypertensive drugs; systolic and/or diastolic blood pressure levels > or = 160 and 95 mmHg, respectively, measured by the general practitioners of the patients before the onset of the subarachnoid haemorrhage; and the presence of left ventricular hypertrophy determined by echocardiography and/or necropsy. The major findings were as follows: 1) hypertension was present in at least 41% of the patients; 2) in 37% of 51 patients with no history of hypertension before the haemorrhage, left ventricular hypertrophy was diagnosed; and 3) the frequency of hypertension was significantly higher in patients who died within 14 days after the bleeding episode compared with patients surviving this period.
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Toftdahl et al. (1995) studied this question.