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April 7, 2011Internal Medicine Journal

Measurement properties of the 6‐min walk test in individuals with exercise‐induced pulmonary arterial hypertension

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Why the study?

Does the encouraged 6-minute walk test validly estimate aerobic capacity and identify exercise limitation in subjects with exercise-induced pulmonary arterial hypertension?

Population

37 adults, comprising 17 subjects with exercise-induced pulmonary arterial hypertension and 20 healthy…

Comparison

Two encouraged 6-minute walk tests and a… vs Healthy controls undergoing the same exercise…

Design

Cross-sectional

Authors

RFRobin FowlerCurtin UniversitySJS JenkinsSir Charles Gairdner HospitalAMAndrew MaioranaHeart Failure & Transplant

Discussion

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Implication

May support 6MWT work to estimate aerobic capacity in EIPAH; hypothesis-generating, requires prospective validation.

Structured PICO

Does the encouraged 6-minute walk test validly estimate aerobic capacity and identify exercise limitation in subjects with exercise-induced pulmonary arterial hypertension?

P
Population
37 adults, comprising 17 subjects with exercise-induced pulmonary arterial hypertension (EIPAH) (mean age 56 ± 14 years, 15 women) and 20 healthy controls (mean age 57 ± 13 years, 19 women).
I
Intervention
Two encouraged 6-minute walk tests (6MWT) and a symptom-limited cardiopulmonary exercise test (CPET) with a pulmonary artery catheter in situ for EIPAH subjects.
C
Comparator
Healthy controls undergoing the same exercise tests (without pulmonary artery catheter).
O
Outcome
Correlation between 6-minute walk distance (6MWD) or 6-minute walk work (6MWW) and peak aerobic capacity (peak VO2) and peak cardiac output (CO).surrogate

The encouraged 6-minute walk test provides a valid estimate of aerobic capacity and identifies reduced exercise capacity in patients with exercise-induced pulmonary arterial hypertension.

Cite This Study

Fowler et al. (2011) studied this question.

synapsesocial.com/papers/6a1a7e8be916fa6dd3b8a963https://doi.org/10.1111/j.1445-5994.2011.02501.x
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