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October 1, 2005European Respiratory JournalOpen Access

Physiological response to the six-minute walk test in pulmonary arterial hypertension

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Why the study?

Does the 6-minute walk test elicit different metabolic stress and aerobic capacity compared to symptom-limited incremental maximal exercise testing in patients with pulmonary arterial hypertension?

Population

20 patients with pulmonary arterial hypertension (PAH)

Comparison

6-minute walk test (6MWT) vs Symptom-limited incremental maximal exercise…

Design

Cross-sectional

Authors

GDGaël DeboeckUniversité Libre de Bruxelles

Discussion

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Implication

6MWT may capture higher aerobic capacity at lower stress than CPET in PAH; leaves open test equivalence for functional assessment.

Structured PICO

Does the 6-minute walk test elicit different metabolic stress and aerobic capacity compared to symptom-limited incremental maximal exercise testing in patients with pulmonary arterial hypertension?

P
Population
20 patients with pulmonary arterial hypertension (PAH)
I
Intervention
6-minute walk test (6MWT)
C
Comparator
Symptom-limited incremental maximal exercise testing (cardiopulmonary exercise test)
O
Outcome
Ventilatory variables (ventilation, O2 consumption, CO2 production, respiratory quotient) and heart ratesurrogate

Patients with pulmonary arterial hypertension exercise at a higher aerobic capacity but lower metabolic stress during the 6-minute walk test compared to a maximal cardiopulmonary exercise test.

Cite This Study

Gaël Deboeck (2005) studied this question.

synapsesocial.com/papers/6a81838b2bdcf510039ce452https://doi.org/10.1183/09031936.05.00031505
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Six-minute walk test in pulmonary arterial hypertension2015 · 100 citations
  2. 2Measurement properties of the 6‐min walk test in individuals with exercise‐induced pulmonary arterial hypertension2011 · 10 citations
  3. 3Six-Minute Walk Test in Evaluation of Children with Pulmonary Arterial Hypertension2017 · 12 citations
  4. 4Six-Minute Walk Distance-derived Estimated Peak Oxygen Uptake as a Supplementary Reference for Exercise Prescription in Pulmonary Arterial Hypertension: A Case Report2026
  5. 5A65-12 Supplemental Oxygen Decreases Cardiac Effort in Pulmonary Arterial Hypertension2026