What question did this study set out to answer?

This study aimed to analyze recurrence patterns and survival outcomes in patients with HR-positive/HER2-negative early breast cancer after curative surgery.

May 30, 2026Journal of Clinical Oncology

Recurrence patterns and survival in hormone receptor-positive/HER2-negative early breast cancer: A retrospective analysis from a public oncologic institution in Peru.

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This study aimed to analyze recurrence patterns and survival outcomes in patients with HR-positive/HER2-negative early breast cancer after curative surgery.
Retrospective cohort study of HR-positive/HER2-negative early breast cancer patients from 2020 to 2024
Included 139 patients with first recurrence after curative-intent surgery
Used Kaplan-Meier and Cox models to estimate time to recurrence and overall survival.
Probabilities of time to recurrence were 88% at 1 year, 60% at 3 years, and 37% at 5 years (median TTR, 48 months)
Overall survival rates at 1, 3, and 5 years were 100%, 95%, and 84% respectively
T3-T4 tumors were linked to a higher risk of death (HR: 1.87, p = 0.026).

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Implication

Retrospective analysis describes recurrence and survival in HR-positive/HER2-negative early breast cancer, suggesting a need for better treatment access.

Cite This Study

Valencia et al. (2026) studied this question.

synapsesocial.com/papers/6a1a7fef0307b7850943207c https://doi.org/10.1200/jco.2026.44.16_suppl.e23402

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Implication

Retrospective analysis describes recurrence and survival in HR-positive/HER2-negative early breast cancer, suggesting a need for better treatment access.

Recurrence patterns and survival in hormone receptor-positive/HER2-negative early breast cancer: A retrospective analysis from a public oncologic institution in Peru.

Key Points

Discussion

Implication

Cite This Study

Recurrence patterns and survival in hormone receptor-positive/HER2-negative early breast cancer: A retrospective analysis from a public oncologic institution in Peru.

Key Points

Discussion

Implication

Cite This Study

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