What question did this study set out to answer?

The study aims to determine factors associated with early and late recurrence in hormone receptor-positive breast cancer.

April 12, 2026BMC CancerOpen Access

Clinical and biomarker predictors of early and late recurrence in hormone receptor-positive breast cancer

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The study aims to determine factors associated with early and late recurrence in hormone receptor-positive breast cancer.
Conducted a retrospective analysis of HR+/HER2- breast cancer cases diagnosed from 1981 to 2022.
Included 4,367 women, assessing variables like metastatic sites and recurrence timing.
Analyzed invasive disease-free survival rates and characteristics of recurrences.
Five-year invasive disease-free survival rate was 85%, while the ten-year rate was 70%.
Early recurrences showed higher nodal involvement and tumor grades compared to late recurrences.
Distant metastases occurred in 70.2% of recurrences, often linked to higher tumor burden and elevated Ki-67 levels.

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Implication

This retrospective analysis identifies clinical and biomarker factors linked to recurrence timing in hormone receptor-positive breast cancer, suggesting implications for management.

Cite This Study

Walbaum et al. (2026) studied this question.

synapsesocial.com/papers/69db37f94fe01fead37c6211 https://doi.org/10.1186/s12885-026-15998-0

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Implication

This retrospective analysis identifies clinical and biomarker factors linked to recurrence timing in hormone receptor-positive breast cancer, suggesting implications for management.

Clinical and biomarker predictors of early and late recurrence in hormone receptor-positive breast cancer

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Discussion

Implication

Cite This Study

Clinical and biomarker predictors of early and late recurrence in hormone receptor-positive breast cancer

Key Points

Discussion

Implication

Cite This Study

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