Why the study?
Do young patients with premature hypertension have abnormal urinary glucocorticoid and androgen excretion profiles compared to older hypertensive patients and normotensive controls?
Do young patients with premature hypertension have abnormal urinary glucocorticoid and androgen excretion profiles compared to older hypertensive patients and normotensive controls?
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Young patients with premature hypertension exhibit abnormally high urinary excretion of glucocorticoid and androgen metabolites, suggesting that partial glucocorticoid receptor resistance may contribute to the pathogenesis of their elevated blood pressure.
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P. Nihoyannopoulos (2001) studied this question.
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