Why the study?
Does transluminal induction of focal septal infarction reduce intraventricular pressure gradients in patients with hypertrophic obstructive cardiomyopathy?
Does transluminal induction of focal septal infarction reduce intraventricular pressure gradients in patients with hypertrophic obstructive cardiomyopathy?
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Transluminal induction of focal septal infarction is a novel, well-tolerated, and effective nonsurgical treatment for reducing left ventricular outflow obstruction in hypertrophic obstructive cardiomyopathy.
We describe a novel treatment for hypertrophic obstructive cardiomyoparhy, in which septal reduction is achived via transluminal induction of focal septal infarction. The results of the first three patients treated in this fashion have been recently reported; in this preliminary series, intraventricular pressure gradients could be dramatically reduced by the creation of a localized infarction of the ventricular septum. The procedure is well tolerated and effective in reducing the obstruction to left ventricular ourflow. Further studies are underway to fully evaluate the usefulness of the technique . (J Interven Cardiol 1996;9:393–397)
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Knight et al. (1996) studied this question.
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