Why the study?
Concomitant coronary artery bypass grafting and pericardiectomy can be a technically challenging operation, and outcomes in these patients required investigation.
Does concomitant coronary artery bypass grafting increase morbidity or mortality in patients undergoing pericardiectomy compared to isolated pericardiectomy?
Does concomitant coronary artery bypass grafting increase morbidity or mortality in patients undergoing pericardiectomy compared to isolated pericardiectomy?
Concomitant CABG during pericardiectomy does not significantly increase in-hospital or long-term mortality compared to isolated pericardiectomy, suggesting CABG should not be denied when indicated.
Answers are grounded in this paper and cite their sources.
Concomitant CABG showed no mortality increase in this cohort; leaves open whether it can be added when indicated pending prospective data.
ObjectiveConcomitant coronary artery bypass grafting (CABG) and pericardiectomy (PC) can be a technically challenging operation. We sought to study the outcomes of patients undergoing concomitant PC and CABG.MethodsBetween July 1983 and August 2016, 70 patients (median age, 67 years; 88% males) underwent concomitant PC and CABG (PC + CABG group). Multivariable analysis was used to identify predictors of mortality. Matched patients who underwent isolated PC (PC group) were identified, and postoperative outcomes and long-term survival in the 2 groups were compared.ResultsCompared with the PC group, cardiopulmonary bypass time was significantly longer in the PC + CABG group (82 minutes vs 61 minutes; P < .001). In-hospital mortality was 4% in the PC group and 7% in the PC + CABG group (P = .380). Multivariable analysis identified peripheral vascular disease (hazard ratio [HR], 2.67; 95% CI, 1.06-6.76; P = .04) as a predictor of increased morbidity or mortality and a borderline association with New York Heart Association functional classes III and IV (HR, 2.41; 95% CI, 0.99-5.86; P = .05) with increased morbidity and mortality in the PC + CABG group. Kaplan–Meier estimates demonstrated similar late mortality rates in the 2 groups at a 15-year follow-up (P = .700).ConclusionsConcomitant PC and CABG is not associated with increased morbidity or mortality compared with isolated PC. Thus, CABG should not be denied at the time of PC.
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Khullar et al. (2022) studied this question.
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