October 7, 2005European Heart Journal
Bundle-branch block in middle-aged men: risk of complications and death over 28 years
Why the study?
Does the presence of bundle-branch block increase the risk of cardiovascular complications and death in middle-aged men?
Population
7,392 men without a history of myocardial infarction or stroke, born between 1915 and 1925, including 70…
Comparison
Presence of right bundle-branch block or left… vs Men without bundle-branch block
Design
Cohort
Follow-up
up to 28 years (from 1970-1973 until 1998)
Authors
Discussion
Loading...
Member takes
Implication
Highlights left BBB as potential risk marker in middle-aged men; leaves open whether it should influence management without randomized data.
Structured PICO
Does the presence of bundle-branch block increase the risk of cardiovascular complications and death in middle-aged men?
P
Population
7,392 men without a history of myocardial infarction or stroke, born between 1915 and 1925, including 70 with right-BBB and 46 with left-BBB at baseline.
I
Intervention
Presence of right bundle-branch block (RBBB) or left bundle-branch block (LBBB)
C
Comparator
Men without bundle-branch block
O
Outcome
Myocardial infarction, coronary death, heart failure, all-cause mortality, and progression to high-degree atrioventricular blockhard clinical
Left bundle-branch block in middle-aged men is strongly associated with future high-degree AV block and an increased risk of coronary death, mainly due to sudden death outside the hospital.
Cite This Study
Eriksson et al. (2005) studied this question.