Key result
Right bundle branch block was associated with an increased risk of all-cause mortality in the general population (HR 1.17; 95% CI 1.03-1.33) compared with no bundle branch block.
Why the study?
Does right bundle branch block increase the risk of mortality and cardiovascular events in the general population and patients with heart disease?
Population
19 prospective cohort studies including 201,437 participants
Comparison
Right bundle branch block (RBBB) at baseline vs No bundle branch block
Design
Meta-analysis
Follow-up
mean follow-up ranging from 1 to 246 months
Authors
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RBBB may warrant closer monitoring in general populations; leaves open whether it is causal or modifiable by intervention.
Meta-Analysis (n=201,437)
Does right bundle branch block increase the risk of mortality and cardiovascular events in the general population and patients with heart disease?
Hazard Ratio: 1.17 (95% CI 1.03–1.33)
Right bundle branch block is a significant prognostic marker associated with increased mortality risk in both the general population and patients with underlying heart disease.
Xiong et al. (2015) conducted a meta-analysis in General population and patients with heart disease (n=201,437). Right bundle branch block (RBBB) vs. No bundle branch block was evaluated on All-cause mortality in the general population (HR 1.17, 95% CI 1.03-1.33). Right bundle branch block was associated with an increased risk of all-cause mortality in the general population (HR 1.17; 95% CI 1.03-1.33) compared with no bundle branch block.
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