September 25, 2006Journal of Internal Medicine
Right bundle branch block and long‐term mortality in patients with acute congestive heart failure
Key result
Right bundle branch block was associated with increased 720-day all-cause mortality compared to no RBBB (63% vs. 39%; HR 2.18, 95% CI 1.26-3.66; P=0.003).
Why the study?
Does the presence of right bundle branch block (RBBB) predict long-term mortality in patients presenting with acute congestive heart failure?
Population
192 consecutive patients presenting with acute congestive heart failure to the emergency department, mean…
Comparison
Presence of right bundle branch block on initial… vs Absence of right bundle branch block (RBBB).
Design
Cohort
Follow-up
720 days
Authors
Discussion
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Implication
RBBB signals elevated long-term mortality risk in ACHF; leaves open its added value for risk stratification beyond current models.
Study Design
Type
Cohort (n=192)
Structured PICO
Does the presence of right bundle branch block (RBBB) predict long-term mortality in patients presenting with acute congestive heart failure?
P
Population
192 elderly patients (mean age 74 years) presenting with acute congestive heart failure to the emergency department, followed for 720 days.
E
Exposure
Presence of right bundle branch block (RBBB) on initial 12-lead electrocardiogram.
C
Comparator
Absence of right bundle branch block (RBBB).
O
Outcome
All-cause mortality during 720-day follow-up.hard clinical
Main Result
Hazard Ratio: 2.18 (95% CI 1.26–3.66)
Absolute Event Rate: 63% vs 39%
p-value: p=0.003
The presence of right bundle branch block on the initial ECG is a strong, independent predictor of long-term mortality in patients presenting with acute congestive heart failure.
Cite This Study
Mueller et al. (2006) conducted a cohort in Acute congestive heart failure (n=192). Right bundle branch block vs. No right bundle branch block was evaluated on All-cause mortality during 720-day follow-up (HR 2.18, 95% CI 1.26-3.66, p=0.003). Right bundle branch block was associated with increased 720-day all-cause mortality compared to no RBBB (63% vs. 39%; HR 2.18, 95% CI 1.26-3.66; P=0.003).