What does this research mean for the field?

Genetic factors account for 13% to 23% of the phenotypic variance in heart rate and heart rate variability measures, indicating that autonomic nervous system activity is substantially heritable. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

May 4, 1999Circulation

Heritability of Heart Rate Variability

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Population

Subjects undergoing ambulatory recordings at a routine examination, excluding those with congestive heart failure, coronary artery disease, diabetes mellitus, and those taking cardioactive medications (n=682 siblings and 206 spouse pairs).

Outcome

Heritability of heart rate and heart rate variability (high-frequency power, low-frequency power, very low-frequency power, total power, low-frequency/high-frequency ratio, and standard deviation of normal R-R intervals)surrogate

Genetic factors account for a significant proportion (13-23%) of the variance in heart rate and heart rate variability, highlighting the heritable contribution to autonomic nervous system activity.

Authors

JSJagmeet SinghHarvard University MLMartin G. LarsonSemmelweis University COChristopher J. O’DonnellGeneral / Preventive / Lipids

Discussion

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Implication

Supports moderate HR/HRV heritability; extends family studies but leaves clinical translation open.

Cite This Study

Singh et al. (1999) studied this question.

synapsesocial.com/papers/6a1ab0bb5448f1e38b45f425 https://doi.org/10.1161/01.cir.99.17.2251

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Heritability of Heart Rate Variability

Structured PICO

Discussion

Implication

Cite This Study

Heritability of Heart Rate Variability

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider