Key result
High levels of total physical activity, cycling, and domestic work were associated with a reduced risk of coronary heart disease in older adults (HR 0.71; 95% CI 0.58-0.87 for high total activity).
Why the study?
Do specific types of physical activity reduce the risk of coronary heart disease in middle-aged and elderly persons?
Cohort (n=5,901)
Do specific types of physical activity reduce the risk of coronary heart disease in middle-aged and elderly persons?
Effect estimate: HR 0.71 (95% CI 0.58-0.87)
In older adults, higher levels of total physical activity, specifically cycling and domestic work, are associated with a significantly reduced risk of coronary heart disease.
May inform activity guidance for older adults; hypothesis-generating and leaves causality open pending trials.
Physical activity is associated with decreased risk of coronary heart disease (CHD). The specific physical activity types that provide beneficial effects in an older population remain unclear. We assessed the association of total physical activity, walking, cycling, domestic work, sports, and gardening with CHD by using Cox proportional hazard models among 5,901 participants aged >55 (median age, 67) years from the prospective population-based Rotterdam Study, enrolled between 1997 and 2001. Activities were categorized into tertiles, and the lowest tertiles were used as reference. In the multivariable model, we adjusted for age, sex, smoking, alcohol consumption, education, diet, and other physical activity types. During 15 years of follow-up (median, 10.3 (interquartile range, 8.0-11.8) years), 642 participants (10.9%) experienced a CHD event. In the multivariable model, the respective hazard ratios for the medium and high categories compared with the low category were 0.79 (95% confidence interval CI): 0.66, 0.96) and 0.71 (95% CI: 0.58, 0.87) for total physical activity, 0.76 (95% CI: 0.63, 0.92) and 0.70 (95% CI: 0.57, 0.88) for cycling, and 0.81 (95% CI: 0.66, 0.98) and 0.71 (95% CI: 0.56, 0.90) for domestic work. Walking, sports, and gardening were not associated with CHD. In conclusion, in this long-term follow-up study of older adults, domestic work and cycling were associated with reduced CHD risk. Physical activity should be promoted in this population with the aim to prevent CHD.
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Koolhaas et al. (2016) conducted a cohort in Coronary heart disease (n=5,901). Physical activity (total, cycling, domestic work) vs. Lowest tertile of physical activity was evaluated on Coronary heart disease event (HR 0.71, 95% CI 0.58-0.87). High levels of total physical activity, cycling, and domestic work were associated with a reduced risk of coronary heart disease in older adults (HR 0.71; 95% CI 0.58-0.87 for high total activity).
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