Key result
Moderate physical activity linked to attenuated but persistent excess CHD risk in high-risk adults.
Why the study?
The study was conducted to evaluate the association between physical activity and the incidence of CHD in individuals with and without CHD risk factors.
Does physical activity reduce incident CHD events in adults with CHD risk factors?
Cohort (n=29,333)
Yes
Does physical activity reduce incident CHD events in adults with CHD risk factors?
Moderate physical activity attenuates but does not completely eliminate the excess risk of coronary heart disease in adults with established cardiovascular risk factors.
No takes yet. Share an insight, caveat, or question.
Activity may partially offset excess CHD risk in those with risk factors; hypothesis-generating and should not yet alter practice.
Smidt et al. (2022) conducted a cohort in Coronary heart disease (n=29,333). Physical activity vs. Physical inactivity was evaluated on Incident CHD events (non-fatal and fatal). Moderate physical activity attenuated but did not eliminate excess CHD risk among adults with risk factors, reducing excess risk from 47% to 21% in obesity and from 152% to 109% in smokers.
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