Key result
Serum FABP4 levels were significantly elevated in AMI patients resuscitated from out-of-hospital cardiac arrest (median 130.2 ng/mL) compared to those without cardiac arrest (median 26.1 ng/mL).
Why the study?
Are serum FABP4 levels elevated in patients with acute myocardial infarction and associated with out-of-hospital cardiac arrest?
Population
106 patients presenting to the emergency unit with a final diagnosis of acute myocardial infarction…
Design
Cohort
Authors
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May indicate adrenergic overdrive in AMI with OHCA; hypothesis-generating for FABP4 as biomarker, needs prospective validation.
Observational (n=106)
Are serum FABP4 levels elevated in patients with acute myocardial infarction and associated with out-of-hospital cardiac arrest?
Absolute Event Rate: 130.2% vs 26.1%
Serum FABP4 levels peak early in AMI and are markedly elevated in patients with out-of-hospital cardiac arrest, suggesting it may serve as a marker of adrenergic overdrive.
Obokata et al. (2016) conducted an observational in Acute myocardial infarction (n=106). Serum FABP4 levels vs. AMI patients without out-of-hospital cardiac arrest was evaluated on Serum FABP4 levels in patients with vs without out-of-hospital cardiac arrest. Serum FABP4 levels were significantly elevated in AMI patients resuscitated from out-of-hospital cardiac arrest (median 130.2 ng/mL) compared to those without cardiac arrest (median 26.1 ng/mL).
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