Why the study?
The authors hypothesized that more severe and extensive coronary atherosclerosis would result in more pronounced myocardial injury and necrosis, leading them to investigate the relationship between serum H-FABP levels and CAD severity.
Are higher serum H-FABP levels associated with more severe and extensive coronary artery disease in patients with acute myocardial infarction?
Are higher serum H-FABP levels associated with more severe and extensive coronary artery disease in patients with acute myocardial infarction?
Answers are grounded in this paper and cite their sources.
Serum H-FABP levels may serve as a biomarker for the severity and extent of coronary atherosclerosis in patients presenting with acute myocardial infarction.
Aim: Heart-type fatty acid binding protein (H-FABP), an early marker of cardiac necrosis, is released rapidly from myocardium as a consequence of ischemic injury. We hypothesized that more severe and extensive coronary atherosclerosis would result in more pronounced myocardial injury and necrosis in patients with acute myocardial infarction (AMI). Therefore, we sought the relationship between serum H-FABP levels and the severity and extent of coronary artery disease (CAD) assessed using the Gensini score.
No takes yet. Share an insight, caveat, or question.
Evrın et al. (2019) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: