Key result
In healthy subjects evaluated by 3-tesla cardiovascular magnetic resonance imaging, right ventricular wall motion abnormalities were evident in 90.8% of patients, predominantly in the apicolateral segments.
Observational (n=65)
No
Right ventricular wall motion abnormalities are common in healthy subjects on 3T CMR and should be recognized as nonpathological variants to avoid misdiagnosis of conditions like ARVD.
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RV wall motion abnormalities on 3T CMR warrant caution to avoid ARVC misdiagnosis; supports normal-variant recognition but leaves open prospective validation.
BACKGROUND: Right ventricular (RV) shape and function serves as an indicator in several types of heart disease such as arrhythmogenic right ventricular dysplasia (ARVD). However, there is no in-depth knowledge of RV motion, even in healthy subjects. The aim of our study was to provide a quantitative analysis of normal variations in RV wall motion in healthy subjects by cardiac magnetic resonance imaging (CMRI). MATERIAL AND METHODS: The study population consisted of 65 consecutive patients referred for the evaluation of cardiac function by 3 Tesla CMR. Balanced steady-state free-precession images were obtained and areas of disordered RV wall motion were evaluated and classified based on a standardised segmental model for the right ventricle. RESULTS: In 59 patients (90.8 %) wall motion abnormalities (WMA) of the right ventricle were evident. WMA were predominately detected in the apicolateral segments (72 %) compared with mediolateral (24 %, P < 0.001) and inferolateral segments (4 %, P < 0.001). Dyskinesia was the most frequent wall motion disorder (62.4 %), followed by hypokinesia (20.8 %) and bulging (16.8 %). The mean WMA diameter in the transverse plane (6.4 ± 1.9 mm) was significantly shorter compared with the diameter in the horizontal long-axis (8.1 ± 3.6 mm, P = 0.002) and short-axis plane (10.7 ± 4.6 mm). CONCLUSION: WMA of the right ventricle are common. Therefore, one should be aware that these nonpathological wall motion disorders can easily be mistaken for a pathological regional wall motion contraction, particularly in ARVD where to date, clear wall motion criteria are lacking.
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Quick et al. (2014) conducted an observational in Healthy subjects (n=65). 3-tesla cardiovascular magnetic resonance imaging was evaluated on Right ventricular wall motion abnormalities (WMA). In healthy subjects evaluated by 3-tesla cardiovascular magnetic resonance imaging, right ventricular wall motion abnormalities were evident in 90.8% of patients, predominantly in the apicolateral segments.
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