Why the study?
What are the circulatory manifestations and risk factors associated with acute cerebrovascular disease compared to matched controls?
What are the circulatory manifestations and risk factors associated with acute cerebrovascular disease compared to matched controls?
Acute cerebrovascular disease in older patients is strongly associated with hypertension and generalized atherosclerosis, indicated by a heavy accumulation of primary cardiovascular risk factors.
Multiple CV risk factors associate with cerebrovascular disease in older adults; extends case-control data but leaves open prospective prediction and causality.
The occurrence of various circulatory manifestations and risk factors was evaluated in a consecutive series of 209 patients admitted for acute cerebrovascular disease (CVD) and 209 control patients admitted for acute surgical disorders. Old and recent myocardial infarction, atrial fibrillation, congestive heart failure and reduced arterial blood pressure in the big toe were all much more frequently noted in CVD patients than in their matched controls. Hypertension, diabetes mellitus, overweight, high haemoglobin values, were also overrepresented in the CVD patients. Male CVD patients had a higher alcohol consumption than their controls. These findings implicate that CVD in old age is strongly related to both hypertension and a generalized atherosclerosis. The heavy accumulation of primary risk factors, many of which are considered to be primarily associated with atherosclerosis among elderly stroke victims, may indicate their contribution to a progressive atherosclerotic process still in operation.
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Arbin et al. (1985) studied this question.
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