Key result
The combination of RAVI, right ventricular parasternal diameter, and RV E/A >0.75 predicted stress-induced LVDD (masked HFpEF) with an accuracy of 91.2% in non-severe COPD patients.
Why the study?
To evaluate the predictive value of resting inflammatory, oxidative stress, cardiopulmonary, and echocardiographic parameters for diagnosing stress-induced LVDD (masked HFpEF) in non-severe COPD patients with exertional dyspnea and no overt cardiovascular disease.
What are the independent predictors of stress-induced left ventricular diastolic dysfunction (masked HFpEF) in non-severe COPD patients with exertional dyspnea?
Observational (n=104)
What are the independent predictors of stress-induced left ventricular diastolic dysfunction (masked HFpEF) in non-severe COPD patients with exertional dyspnea?
Effect estimate: Accuracy 91.2%
In non-severe COPD patients with exertional dyspnea, masked HFpEF is highly prevalent and can be accurately predicted by resting right heart echocardiographic parameters.
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May aid masked HFpEF detection via resting right heart echo in non-severe COPD; leaves open prospective validation.
Cherneva et al. (2021) conducted an observational in Non-severe chronic obstructive pulmonary disease (COPD) (n=104). Echocardiographic parameters (RAVI, right ventricular parasternal diameter, RV E/A) was evaluated on Stress induced left ventricular diastolic dysfunction (LVDD) / masked HFpEF (Accuracy 91.2%). The combination of RAVI, right ventricular parasternal diameter, and RV E/A >0.75 predicted stress-induced LVDD (masked HFpEF) with an accuracy of 91.2% in non-severe COPD patients.
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