Key result
Diastolic dysfunction in patients with COPD was associated with increased length of hospital stay (4.02 vs 3.24 days; P=0.005) and more frequent exacerbations (1.28 vs 0.67 per year; P=0.0067).
Why the study?
Does the presence of diastolic dysfunction increase the duration of hospitalization and frequency of exacerbations in patients with COPD?
Cohort (n=139)
Does the presence of diastolic dysfunction increase the duration of hospitalization and frequency of exacerbations in patients with COPD?
Absolute Event Rate: 4.02% vs 3.24%
p-value: p=0.005
In patients with COPD, the presence of diastolic dysfunction is associated with significantly longer hospital stays and more frequent hospitalizations for exacerbations.
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Diastolic dysfunction may aid risk stratification in COPD; hypothesis-generating and requires prospective confirmation before changing practice.
Abusaid et al. (2009) conducted a cohort in COPD exacerbation (n=139). Diastolic dysfunction vs. Normal diastolic function was evaluated on Length of hospital stay in days (p=0.005). Diastolic dysfunction in patients with COPD was associated with increased length of hospital stay (4.02 vs 3.24 days; P=0.005) and more frequent exacerbations (1.28 vs 0.67 per year; P=0.0067).
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