Key result
Controlled hypoxaemia (SaO2 75-80%) significantly prolonged left ventricular corrected relaxation time compared to baseline (mean difference 9.8 ms; 95% CI 1-19).
Why the study?
Does induced hypoxaemia impair right and left ventricular diastolic function in healthy male subjects?
Does induced hypoxaemia impair right and left ventricular diastolic function in healthy male subjects?
Mean Difference: 9.8 (95% CI 1–19)
Acute hypoxaemia significantly impairs both left and right ventricular diastolic relaxation in healthy humans.
No takes yet. Share an insight, caveat, or question.
May warrant caution during severe hypoxaemia; leaves open effects in patients with cardiopulmonary disease.
Cargill et al. (1995) studied Healthy (n=10). Hypoxaemia vs. Baseline was evaluated on Left ventricular isovolumic relaxation time corrected for heart rate (MD 9.8 ms, 95% CI 1-19). Controlled hypoxaemia (SaO2 75-80%) significantly prolonged left ventricular corrected relaxation time compared to baseline (mean difference 9.8 ms; 95% CI 1-19).
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