Why the study?
Do adrenergic signaling polymorphisms affect cardiovascular disease risk or therapeutic response to beta-blockers?
Do adrenergic signaling polymorphisms affect cardiovascular disease risk or therapeutic response to beta-blockers?
The clinical relevance of individual genotyping for most adrenergic pathway polymorphisms remains uncertain due to conflicting data.
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Clinical utility of genotyping most adrenergic polymorphisms remains uncertain; leaves open whether select variants warrant targeted CVD risk or beta-blocker studies.
Gerald W. Dorn (2010) studied this question.
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