Thrombus characteristics evaluated by acute optical coherence tomography in ST elevation myocardial Infarction

Figures

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  Fig 1. Flowchart.

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  Fig 2. Comparison between ratio of lightloss measured by Ilumien Optis and ImageJ softwares with correlation 0,40 (p = 0,0001).

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  Fig 3. Ratio of lightloss by Ilumien Optis software in the different histopathological defined colours.

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  Fig 4. Ratio of lightloss by Ilumien Optis software in thrombi defined by histopathological appearance.

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  Fig 5. The same thrombus (arrow) as it appears on ImageJ (A) and Ilumien Optis (B) softwares. Thrombus protruding towards catheter appears compressed in ImageJ (A). Size of ROI (Region of Interest) showed in red figures (a = small ROI, b = large ROI, c = freehand ROI). Ratio of lightloss in these images was 1.02 by ImageJ and 0.64 by Ilumien Optis. Diameter of catheter is 0.914 microns.

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  Fig 6. Representative image of fresh thrombus, classified as a red thrombus (in this case 80% of erythrocytes) in HE staining (A), red area represents erythrocytes; Inset: a higher magnification image (B) showing the interface of small area of platelet aggregates (pale pink staining) with red blood cells and granulocytes (dark purple nucleated cells). Images are from the same patient as Fig 5. Bar scale in A: 200 μm and in B: 25 μm.