Why the study?
Do hypertension and prehypertension adversely affect cardiac structure and hemodynamics in adolescents and young adults?
Population
1,940 participants, 14 to 39 years of age, in the Strong Heart Study
Comparison
Hypertension (n=294) and prehypertension (n=675) vs Normotensive participants
Design
Cross-sectional
Key result
Hypertension and prehypertension in adolescents and young adults were associated with higher left ventricular mass (182 and 161 vs 137 g) and 3- and 2-fold higher prevalences of LVH (P<0.001).
Authors
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May indicate early cardiac effects of elevated BP in youth; hypothesis-generating for longitudinal and interventional studies.
Observational (n=1,940)
Do hypertension and prehypertension adversely affect cardiac structure and hemodynamics in adolescents and young adults?
p-value: p=<0.001
Even in adolescents and young adults, prehypertension and hypertension are associated with adverse preclinical cardiovascular changes, including left ventricular hypertrophy and increased arterial stiffness.
Drukteinis et al. (2007) conducted an observational in Hypertension and Prehypertension (n=1,940). Hypertension and Prehypertension vs. Normotension was evaluated on Left ventricular structure and function, and hemodynamic parameters (p=<0.001). Hypertension and prehypertension in adolescents and young adults were associated with higher left ventricular mass (182 and 161 vs 137 g) and 3- and 2-fold higher prevalences of LVH (P<0.001).