Key result
Prehypertension in youth was associated with unfavorable, race-dependent cardiovascular phenotypes, including increased radial pulse-wave velocity in white subjects (6.8 vs 6.2 m/sec; P<0.001).
Why the study?
Does prehypertension affect cardiovascular structure and function in American youth compared to normotension?
Cohort (n=942)
Does prehypertension affect cardiovascular structure and function in American youth compared to normotension?
Absolute Event Rate: 6.8% vs 6.2%
p-value: p=<0.001
Prehypertension in youth is associated with unfavorable, race-dependent cardiovascular phenotypes, including increased arterial stiffness in whites and higher cardiac index in blacks.
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Supports race-specific phenotyping in prehypertensive youth; leaves open causality and prospective outcome trials.
Zhu et al. (2007) conducted a cohort in Prehypertension (n=942). Prehypertension vs. Normotension was evaluated on Radial pulse-wave velocity in white subjects (m/sec) (p=<0.001). Prehypertension in youth was associated with unfavorable, race-dependent cardiovascular phenotypes, including increased radial pulse-wave velocity in white subjects (6.8 vs 6.2 m/sec; P<0.001).
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