Why the study?
Does the direction of ST-segment shift correlate with the type of ischemic block and mortality in patients with anterior AMI?
Does the direction of ST-segment shift correlate with the type of ischemic block and mortality in patients with anterior AMI?
The direction of ST-segment shift during the hyperacute phase of anterior AMI correlates with the specific type of bundle branch block and is associated with a very high mortality rate.
Answers are grounded in this paper and cite their sources.
ST-segment shift direction may identify ischemic block patterns in anterior AMI; hypothesis-generating and requires prospective validation before clinical use.
Of 760 consecutive cases with anterior acute myocardial infarction (AMI), 55 developed acute bundle-branch block (BBB), fascicular block, or high-degree atrioventricular block during the hyperacute ECG stage of AMI. According to the direction of the ST segment during the acute ischemic episode, patients were divided into two groups. Group A consisted of 32 patients who developed BBB during ST-segment elevation, positive T wave, and absent or minimal Q wave. Group B consisted of 23 patients who developed BBB during ST-segment depression and evolved into anterior AMI. Group A was characterized by a higher incidence of right BBB and left anterior hemiblock [91% vs. 26% and 56% vs. 13%, respectively (p less than 0.005)]. Group B was characterized by a higher incidence of left BBB and left posterior hemiblock [57% vs. 9% and 26% vs. 12%, respectively (p less than 0.001)]. The BBB was transient (disappearing within hours to one day) in 14 patients in Group A and in 5 patients in Group B. The incidence of progression to high-degree atrioventricular block was almost equal in the two groups (25% and 26%). The mortality rate was very high in both groups, but higher in Group B [74% vs. 59% (p = NS)] especially in those with LBBB (85%). Most patients died on the day of occurrence of BBB [Group A, 50% vs. Group B, 70% (p = NS)]. The causes of death in both groups were cardiogenic shock and/or electromechanical dissociation.(ABSTRACT TRUNCATED AT 250 WORDS)
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Sclarovsky et al. (1988) studied this question.
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