Key result
Adequate pre-operative physical activity level was independently associated with short-term mortality (OR 5.5; 95% CI 1.4-21.9) after major oncological abdominal surgery.
Why the study?
Does pre-operative physical fitness and physical activity predict postoperative outcomes in patients undergoing major oncological abdominal surgery?
Observational (n=169)
Does pre-operative physical fitness and physical activity predict postoperative outcomes in patients undergoing major oncological abdominal surgery?
Effect estimate: OR 5.5 (95% CI 1.4-21.9)
Pre-operative physical activity and fitness measurements significantly improve the prediction of postoperative outcomes compared to conventional risk factors.
May aid preoperative mortality risk stratification in oncologic surgery; leaves open causality and intervention effects.
We studied whether reported physical activity and measurements of fitness (hand, leg and inspiration) were associated with postoperative in-hospital mortality, length of stay and discharge destination in 169 patients after major oncological abdominal surgery. In multivariate analysis, adequate activity level (OR 5.5, 95% CI 1.4-21.9) and inspiratory muscle endurance (OR 5.2, 95% CI 1.4-19.1) were independently associated with short-term mortality, whereas conventional factors, such as age and heart disease, were not. Adequate activity level (OR 6.7, 95% CI 1.4-3.0) was also independently associated with discharge destination. The factors that were independently associated with a shorter length of hospital stay were as follows: absence of chronic obstructive pulmonary disease (HR 0.6, 95% CI 0.3-1.1); adequate activity level (HR 0.6, 95% CI 0.4-0.8); and inspiratory muscle strength (HR 0.6, 95% CI 0.5-0.9). For all postoperative outcomes physical activity and fitness significantly improved the predictive value compared with known risk factors, such as age and comorbidities. We conclude that pre-operative questionnaires of physical activity and measurements of fitness contribute to the prediction of postoperative outcomes.
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Dronkers et al. (2012) conducted an observational in major oncological abdominal surgery (n=169). Pre-operative physical activity and fitness was evaluated on short-term mortality (OR 5.5, 95% CI 1.4-21.9). Adequate pre-operative physical activity level was independently associated with short-term mortality (OR 5.5; 95% CI 1.4-21.9) after major oncological abdominal surgery.
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