Key result
Aspiration thrombectomy using the Diver C.E. MAX catheter combined with primary stenting significantly improved complete restoration of ST segment elevation compared to primary stenting alone (90% vs 64%, P < 0.01).
Why the study?
Does aspiration thrombectomy added to primary stenting improve ST segment resolution and LVEF in patients with acute myocardial infarction?
Cross-Sectional (n=136)
No
Does aspiration thrombectomy added to primary stenting improve ST segment resolution and LVEF in patients with acute myocardial infarction?
Aspiration thrombectomy prior to primary stenting in acute myocardial infarction significantly improves epicardial flow and myocardial perfusion, though it has minimal short-term impact on left ventricular ejection fraction.
Answers are grounded in this paper and cite their sources.
May support adjunctive thrombectomy for ST resolution in AMI; leaves open effects on LVEF or outcomes pending RCTs.
Objectives: To evaluate the effects of aspiration thrombectomy (AT) using anAspiration Catheter (INVATEC SPA DIVER C.E. MAX, Italy) in patients with acute myocardialinfarction (AMI). Study Design: Cross sectional and Case series study. Setting: Departmentof Cardiology, Liaquat University Hospital, Hyderabad. Period: January 2012 to December2013. Methodology and Results: Measurement of left ventricular ejection fraction (LVEF) byechocardiography was obtained before (acute LVEF) percutaneous coronary intervention (PCI)and 1 week after (late LVEF) the procedure. Most of the patients with full restoration of STsegment elevation following PCI were higher in the aspiration Catheter control group (90 vs68%, P < 0.01), (86 vs 62%, P < 0.01) and (90 vs 64%, P < 0.01) respectively. Minimal changein LVEF was observed in patients between the Aspiration Catheter group and control group at1 week post procedure. Conclusion: Combination of AT using Aspiration Catheter (INVATECSPA DIVER C.E. MAX) with primary stenting can better outcome, while left ventricle (LV) functionhad subtle change in AMI when compared to primary stenting after balloon predilation withoutthrombectomy.
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Brohi et al. (2018) conducted a cross-sectional in Acute Myocardial Infarction (n=136). Aspiration thrombectomy (DIVER C.E. MAX) with primary stenting vs. Primary stenting alone was evaluated on Complete restoration of ST segment elevation (p=<0.01). Aspiration thrombectomy using the Diver C.E. MAX catheter combined with primary stenting significantly improved complete restoration of ST segment elevation compared to primary stenting alone (90% vs 64%, P < 0.01).
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