Key result
Systolic blood pressure (HR 1.17; 95% CI 1.10-1.24 per 1 SD increment) and pulse pressure are the strongest determinants of major cardiovascular risk in older patients with type 2 diabetes.
Cohort (n=11,140)
Effect estimate: HR 1.17 (95% CI 1.10-1.24)
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May refine CV risk stratification by SBP and pulse pressure in older T2D; leaves open whether targeting them improves outcomes.
Kengne et al. (2009) conducted a cohort in type 2 diabetes mellitus (n=11,140). Baseline blood pressure variables (SBP, DBP, PP, MAP) was evaluated on Major cardiovascular events (HR 1.17, 95% CI 1.10-1.24). Systolic blood pressure (HR 1.17; 95% CI 1.10-1.24 per 1 SD increment) and pulse pressure are the strongest determinants of major cardiovascular risk in older patients with type 2 diabetes.
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