Key result
Electrocardiographic indicators of ventricular repolarization were significantly altered during alcohol withdrawal compared to after symptoms subsided (P=0.001), suggesting increased arrhythmia risk.
Why the study?
The study aimed to examine the potential risk of ventricular arrhythmia and sudden cardiac death by evaluating electrocardiographic changes and ventricular repolarization indicators during and after alcohol withdrawal.
Does alcohol withdrawal affect electrocardiographic indicators of ventricular repolarization compared to after withdrawal symptoms subside?
Observational (n=100)
Does alcohol withdrawal affect electrocardiographic indicators of ventricular repolarization compared to after withdrawal symptoms subside?
p-value: p=0.001
Alcohol withdrawal is associated with transient electrocardiographic changes indicating altered ventricular repolarization, suggesting an increased risk of ventricular arrhythmias during the withdrawal period.
Background: Our study aimed to examine the possible risk of ventricular arrhythmia and sudden cardiac death by calculating the electrocardiographic changes and indicators of ventricular repolarization during and after alcohol withdrawal. Methods: One hundred participants who were identified with alcohol withdrawal and who met the inclusion criteria were included in the study. Data were collected between July 2020 and August 2020. The distance interval between Q and T waves, corrected distance interval between Q and T waves, T peak/distance interval between Q and T waves, and T peak/corrected distance interval between Q and T waves interval ratios ratios were measured in 12-lead electrocardiographic measurements during the withdrawal period and after withdrawal symptoms subsided in patients with a Clinical Institute Withdrawal Assessment of Alcohol Scale, Revised score >7 and a Framingham heart risk score <10%. Results: 001). Conclusion: These consequences suggest the risk for an accelerated hazard of ventricular arrhythmias in participants with alcohol withdrawal. Significantly, considering the improvement of the electrocardiographic changes of the patients after terminating alcohol intake, a possible cardiac arrhythmia may be more common during this period. Close monitoring of electrocardiograms and timely withdrawal treatment can prevent life-threatening arrhythmias in alcohol withdrawal patients.
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İzci et al. (2023) conducted an observational in Alcohol withdrawal (n=100). Alcohol withdrawal period vs. After withdrawal symptoms subsided was evaluated on Electrocardiographic changes and indicators of ventricular repolarization (QT, QTc, Tp-e/QT, Tp-e/QTc) (p=0.001). Electrocardiographic indicators of ventricular repolarization were significantly altered during alcohol withdrawal compared to after symptoms subsided (P=0.001), suggesting increased arrhythmia risk.
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