Key result
Apical hypertrophic cardiomyopathy can present in non-Asian patients with variable clinical expressions, including severe angina and ventricular tachycardia, and may be underdiagnosed.
Case Report (n=2)
Apical hypertrophic cardiomyopathy can present in non-Asian populations with variable clinical manifestations, including severe angina or arrhythmias, and may require ICD placement for primary prevention in high-risk individuals.
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May warrant consideration in non-Asian patients with unexplained angina or VT; leaves open prevalence and risk-stratification needs.
Apical hypertrophic cardiomyopathy (AHCM) has been rarely described in the Western world. More recently, improved sensitivity of diagnostic modalities and increased diagnostic awareness have increased detection rates, suggesting that the prevalence outside of Asia may have been previously understated. Hallmark features of AHCM include deeply negative, "giant" T-wave inversions on electrocardiography and a "spade-like" configuration of the left ventricle on ventriculography. We present two cases of AHCM, one in an African-American female and another in a Caucasian male.
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Kapoor et al. (2016) conducted a case report in Apical Hypertrophic Cardiomyopathy (n=2). Apical hypertrophic cardiomyopathy can present in non-Asian patients with variable clinical expressions, including severe angina and ventricular tachycardia, and may be underdiagnosed.
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