Trajectories of Pre-exposure Prophylaxis Adherence Among Commercially Insured Individuals

Q: What does this research mean for the field?

Less than half (44.5%) of commercially insured PrEP users maintain consistent adherence, with early discontinuation being significantly associated with younger age, female sex, substance use disorder, and depression. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Ikenna Unigwe; Amie Goodin; Wei‐Hsuan Lo‐Ciganic; Robert L. Cook; Haesuk Park

doi:10.1093/cid/ciad756

December 8, 2023Clinical Infectious Diseases

Trajectories of Pre-exposure Prophylaxis Adherence Among Commercially Insured Individuals

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Abstract

We used group-based trajectory models to identify 4 distinct trajectory patterns of adherence to preexposure prophylaxis (PrEP) among 20 696 users. Only 44.5% were consistently PrEP adherent, with younger age, being female, or having substance use disorder or depression associated with early discontinuation. Public health efforts are needed to improve PrEP adherence.

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Unigwe et al. (2023) studied this question.

synapsesocial.com/papers/6a1b44bb39ea7417dc42a365 https://doi.org/10.1093/cid/ciad756

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Trajectories of Pre-exposure Prophylaxis Adherence Among Commercially Insured Individuals

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Abstract

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Trajectories of Pre-exposure Prophylaxis Adherence Among Commercially Insured Individuals

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Abstract

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