Key result
Diabetes was modestly associated with an increased risk of new-onset atrial fibrillation in hypertensive patients without ischemic vascular disease (HR 1.11; 95% CI 1.06-1.16).
Why the study?
Does diabetes increase the risk of new-onset atrial fibrillation in hypertensive patients aged ≥55 years without ischemic vascular disease?
Population
262,892 hypertensive persons aged ≥55 years with no ischemic heart disease, stroke, or peripheral artery…
Comparison
Diabetes mellitus vs No diabetes mellitus
Design
Cohort
Follow-up
mean 4.1 to 4.3 years
Authors
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May inform AF surveillance in diabetic hypertensives; leaves open independent causality and need for trials.
Cohort (n=262,892)
Yes
Does diabetes increase the risk of new-onset atrial fibrillation in hypertensive patients aged ≥55 years without ischemic vascular disease?
Effect estimate: HR 1.11 (95% CI 1.06-1.16)
Absolute Event Rate: 13.3% vs 10.4%
Diabetes is modestly associated with an increased risk of new-onset atrial fibrillation in older hypertensive patients without ischemic vascular disease, with obesity further increasing this risk.
Alves‐Cabratosa et al. (2016) conducted a cohort in Hypertension (n=262,892). Diabetes vs. Non-diabetic was evaluated on New-onset atrial fibrillation (HR 1.11, 95% CI 1.06-1.16). Diabetes was modestly associated with an increased risk of new-onset atrial fibrillation in hypertensive patients without ischemic vascular disease (HR 1.11; 95% CI 1.06-1.16).
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