Key result
Protecting the brachial artery with a blood pressure cuff during weight lifting increased post-exercise flow-mediated dilation in sedentary (10.5% vs 8.7% pre-lift) and trained individuals.
Why the study?
Does protecting the brachial artery from exercise-induced hypertension with a blood pressure cuff prevent post-exercise reduction in flow-mediated dilation in young, healthy subjects?
Does protecting the brachial artery from exercise-induced hypertension with a blood pressure cuff prevent post-exercise reduction in flow-mediated dilation in young, healthy subjects?
Protecting the brachial artery from exercise-induced hypertension during heavy resistance exercise prevents the reduction of flow-mediated dilation, suggesting intraluminal pressure contributes to endothelial impairment.
Should not yet change lifting protocols; leaves open pressure's role in post-exercise endothelial changes.
PURPOSE: The purpose of this study was to determine if increased intraluminal pressure is the damaging factor which reduces flow mediated dilation (FMD) in young, healthy subjects following resistance exercise to maximal exertion. HYPOTHESIS: Attenuating the rise in brachial artery pressure during weight lifting by placing a blood pressure cuff on the upper arm prevents post-exercise impairment of brachial artery FMD in sedentary individuals. METHODS: Nine sedentary individuals who exercise ≤1 time/week and six exercise-trained individuals who exercise ≥3 times/week performed leg press exercise to maximal exertion on two separate occasions. During one visit a blood pressure cuff, proximal to the site of brachial artery measurement, was inflated to 100 mmHg to protect the distal vasculature from the rise in intraluminal pressure which occurs during resistance exercise. Brachial artery FMD was determined using ultrasonography before and 30 minutes after weight lifting. RESULTS: Without the protective cuff, brachial artery FMD in sedentary individuals was reduced after weight lifting (9.0 ± 1.2% pre-lift vs. 6.6 ± 0.8% post-lift; p=0.005) while in exercise-trained individuals FMD was unchanged (7.4 ± 0.7% pre-lift vs. 8.0 ± 0.9% post-lift; p=0.543). With the protective cuff, FMD no longer decreased, but rather increased in sedentary individuals (8.7 ± 1.2% pre-lift vs. 10.5 ± 1.0% post-lift, p=0.025). An increase in FMD was also seen in exercise-trained subjects when the cuff was present (6.6 ±0.7% pre-lift vs. 10.9 ±1.5% post-lift, p<0.001). CONCLUSION: Protecting the brachial artery from exercise-induced hypertension enhances FMD in sedentary and exercise-trained individuals. These results indicate that increased intraluminal pressure in the artery contributes to the reduced FMD following heavy resistance exercise in sedentary individuals.
No takes yet. Share an insight, caveat, or question.
Buchanan et al. (2016) studied Healthy subjects (n=15). Blood pressure cuff inflated proximal to brachial artery measurement site vs. Leg press exercise without protective cuff was evaluated on Brachial artery flow-mediated dilation (FMD). Protecting the brachial artery with a blood pressure cuff during weight lifting increased post-exercise flow-mediated dilation in sedentary (10.5% vs 8.7% pre-lift) and trained individuals.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: