Key result
Normal brain ageing is associated with physiological adaptations in cerebral autoregulation and neurovascular coupling, though studies show conflicting findings regarding vascular activation responses.
Why the study?
With worldwide population ageing and the high burden of cerebrovascular diseases, understanding and promoting healthy vascular brain ageing has become an increasing priority.
Understanding vascular and haemodynamic changes in normal brain ageing is crucial for distinguishing physiological adaptations from pathological states like stroke and dementia.
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May aid differentiation of physiological ageing from stroke or dementia in practice; leaves open resolution of conflicting vascular response data.
Beishon et al. (2021) conducted a review in Brain ageing. Normal brain ageing is associated with physiological adaptations in cerebral autoregulation and neurovascular coupling, though studies show conflicting findings regarding vascular activation responses.
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