Key result
Higher HDL-C, albumin, and lymphocytes predict lower preoperative DVT risk in femur fracture patients.
Why the study?
This study aimed to develop a nomogram to forecast the incidence of preoperative deep vein thrombosis in patients with an intertrochanteric femur fracture.
Can a nomogram based on HDL-C, ALB, and LYM predict the occurrence of preoperative deep vein thrombosis in patients with intertrochanteric femur fractures?
Cohort (n=338)
Yes
Can a nomogram based on HDL-C, ALB, and LYM predict the occurrence of preoperative deep vein thrombosis in patients with intertrochanteric femur fractures?
Effect estimate: OR 0.18 (95% CI 0.04-0.71)
p-value: p=0.014
A nomogram incorporating HDL-C, albumin, and lymphocytes can accurately predict the risk of preoperative deep vein thrombosis in patients with intertrochanteric femur fractures.
May inform nomogram-based preoperative DVT risk stratification in intertrochanteric fractures; leaves open prospective validation before clinical adoption.
BACKGROUND: This study aims to develop a nomogram and forecast the incidence of DVT in individuals suffering from an intertrochanteric femur fracture. METHOD: This work created a nomogram using the R programming language and employed logistic regression to determine independent predicting features. An external validation dataset was used to validate the nomogram. RESULT: The findings demonstrated the independence of LYM (0.02[0.01-0.09], p < 0.001), ALB (0.83[0.74, 0.94], p = 0.002), and HDL-C (0.18[0.04, 0.71], p = 0.014). Good prediction performance with modest errors was shown by the nomogram in both the training and validation groups. CONCLUSION: In conclusion, the nomogram that was created using HDL-C, ALB, and LYM can assist medical professionals in determining the likelihood that DVT will occur.
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Li et al. (2024) conducted a cohort in Intertrochanteric femur fracture (n=338). High-density lipoprotein cholesterol (HDL-C) was evaluated on Occurrence of preoperative deep vein thrombosis (DVT) (OR 0.18, 95% CI 0.04-0.71, p=0.014). High-density lipoprotein cholesterol (OR 0.18), albumin (OR 0.83), and lymphocytes (OR 0.02) independently predicted preoperative deep vein thrombosis in intertrochanteric femur fracture patients.
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