Why the study?
Elevated pulse pressure independently predicts cardiovascular diseases, but prior studies examining its relationship with body mass index have yielded inconsistent findings.
Is elevated body mass index associated with elevated pulse pressure in active-duty military personnel?
Is elevated body mass index associated with elevated pulse pressure in active-duty military personnel?
Pulse pressure is positively associated with BMI in active-duty military personnel, with the association being stronger in those with normal blood pressure compared to those with high blood pressure.
Answers are grounded in this paper and cite their sources.
May link higher BMI to elevated pulse pressure in normotensive military personnel; leaves open causal and prognostic implications.
Background Elevated pulse pressure (PP) is a robust independent predictor of cardiovascular diseases. The relationship between PP and body mass index (BMI) was presented in a few studies. However, the findings were inconsistent. Therefore, the aim of the present study is to identify the association between elevated PP and BMI using a large sample of active-duty Royal Thai Army (RTA) personnel. Methods A cross-sectional study was conducted through the use of the dataset obtained from the annual health examination database of RTA personnel in Thailand in 2022. BMI 25.0–29.9 kg/m 2 was classified as obesity I, whereas BMI ≥ 30.0 kg/m 2 was classified as obesity II. Elevated PP was defined as PP ≥ 50 mmHg. Multivariable linear regression and log-binomial regression models were utilized for determining the association between elevated PP and BMI. Results A total of 62,113 active-duty RTA personnel were included in the study. The average BMI was 25.4 ± 3.8 kg/m 2 , while the average PP was 50.1 ± 11.2 mmHg. Compared to individuals with normal weight, the β β coefficients of PP and BMI were 1.38 (95% CI: 1.15–1.60) and 2.57 (95% CI: 2.25–2.88) in individuals with obesity I and obesity II, respectively. Effect modification by high blood pressure (BP) on the association between elevated PP and BMI was observed. Among participants with normal BP, in comparison with BMI of 18.5–22.9 kg/m 2 , the adjusted prevalence ratio (PR) for elevated PP was 1.23 (95% CI: 1.19–1.28) and 1.41 (95% CI: 1.35–1.48) in those with obesity I and obesity II, respectively. Meanwhile, among individuals with high BP, the adjusted PR for elevated PP was 1.05 (95% CI: 1.01–1.08) and 1.09 (95% CI: 1.06–1.13) in those with obesity I and obesity II, respectively. Conclusion PP was positively associated with BMI in active-duty RTA personnel. High BP was the modifier of the association between PP and BMI. A weaker association between elevated PP and BMI was observed among RTA personnel with high BP.
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Sakboonyarat et al. (2023) studied this question.
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