February 1, 2001HypertensionOpen Access

Ascorbic Acid Status and Subsequent Diastolic and Systolic Blood Pressure

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Why the study?

Does plasma ascorbic acid level correlate with diastolic and systolic blood pressure in men?

Population

68 men aged 30 to 59 years, non-smokers, non-drinkers, with mean diastolic blood pressure of 73.4 mm Hg and…

Design

Other

Follow-up

17 weeks

Authors

GBGladys BlockUniversité Claude Bernard Lyon 1 AMAnn Reed MangelsUniversity of California, Santa Cruz ENEdward P. NorkusMontefiore Medical Center

Discussion

Member takes

Implication

Should not yet change hypertension management; leaves open whether ascorbic acid influences blood pressure.

Structured PICO

Does plasma ascorbic acid level correlate with diastolic and systolic blood pressure in men?

Population

68 men aged 30 to 59 years, non-smokers, non-drinkers, with mean diastolic blood pressure of 73.4 mm Hg and mean systolic blood pressure of 122.2 mm Hg.

Intervention

17-week controlled diet including 1 month of vitamin C depletion followed by 1-month repletion with 117 mg/d, repeated twice.

Outcome

Diastolic and systolic blood pressuresurrogate

Higher plasma ascorbic acid levels are strongly inversely correlated with subsequent diastolic and systolic blood pressure in men.

Cite This Study

Block et al. (2001) studied this question.

synapsesocial.com/papers/6a1bc0c800ee29383e9cd2ba https://doi.org/10.1161/01.hyp.37.2.261

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February 1, 2001HypertensionOpen Access

Ascorbic Acid Status and Subsequent Diastolic and Systolic Blood Pressure

View Full Paper

Ask AI

Bookmark

Why the study?

Does plasma ascorbic acid level correlate with diastolic and systolic blood pressure in men?

Population

68 men aged 30 to 59 years, non-smokers, non-drinkers, with mean diastolic blood pressure of 73.4 mm Hg and…

Design

Other

Follow-up

17 weeks

Authors

GBGladys BlockUniversité Claude Bernard Lyon 1 AMAnn Reed MangelsUniversity of California, Santa Cruz ENEdward P. NorkusMontefiore Medical Center

Discussion

Member takes

Implication

Should not yet change hypertension management; leaves open whether ascorbic acid influences blood pressure.

Structured PICO

Does plasma ascorbic acid level correlate with diastolic and systolic blood pressure in men?

Population

68 men aged 30 to 59 years, non-smokers, non-drinkers, with mean diastolic blood pressure of 73.4 mm Hg and mean systolic blood pressure of 122.2 mm Hg.

Intervention

17-week controlled diet including 1 month of vitamin C depletion followed by 1-month repletion with 117 mg/d, repeated twice.

Outcome

Diastolic and systolic blood pressuresurrogate

Higher plasma ascorbic acid levels are strongly inversely correlated with subsequent diastolic and systolic blood pressure in men.

Cite This Study

Block et al. (2001) studied this question.

synapsesocial.com/papers/6a1bc0c800ee29383e9cd2ba https://doi.org/10.1161/01.hyp.37.2.261

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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