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April 22, 2010DiabetesOpen Access

The Transcription Factor Rfx3 Regulates β-Cell Differentiation, Function, and Glucokinase Expression

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Authors

AAAouatef Ait‐LounisUniversity of GenevaCBClaire BonalNovartis (Switzerland)QSQueralt Seguín-EstévezUniversity of Geneva

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Ait‐Lounis et al. (2010) studied this question.

synapsesocial.com/papers/6a1bc178ea84844e355ee4bdhttps://doi.org/10.2337/db09-0986
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1RFX Proteins, a Novel Family of DNA Binding Proteins Conserved in the Eukaryotic Kingdom1996 · 204 citations
  2. 2Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut.1994 · 282 citations
  3. 3Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic β cells1998 · 632 citations
  4. 4A Consensus Motif in the RFX DNA Binding Domain and Binding Domain Mutants with Altered Specificity1996 · 73 citations
  5. 5Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX42003 · 103 citations