Key result
Intracranial stenting trial data vs. medical therapy remain unreported for symptomatic ICAS.
Why the study?
Does intracranial stenting reduce ischemic events compared to medical therapy in patients with severe symptomatic ICAS without adjacent BAD?
RCT (n=150)
open-label, blinded end-point
randomized
No
Does intracranial stenting reduce ischemic events compared to medical therapy in patients with severe symptomatic ICAS without adjacent BAD?
Endovascular stent placement offers no benefit over medical therapy; reinforces medical management as standard in symptomatic intracranial stenosis without branch atheromatous disease.
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Ip et al. (2025) conducted an RCT in symptomatic intracranial atherosclerotic stenosis (ICAS) (n=150). intracranial stent placement vs. medical therapy was evaluated on composite of TIA, ischemic stroke, intracranial hemorrhage, and death within 30 days or any ischemic stroke from 30 days to 1 year. The results of intracranial stenting versus medical therapy for symptomatic ICAS were not reported due to truncated abstract text.
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