Why the study?
Does adherence to a computerised self-adjusting anticoagulant algorithm improve time in the therapeutic range in patients on oral anticoagulants?
Population
3,660 patients on oral anticoagulants managed in primary care and pharmacies across 60 sites in New Zealand.
Comparison
Computerised self-adjusting anticoagulant… vs Clinician over-ride of the algorithm.
Design
Cohort
Follow-up
3 years
Authors
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Pharmacist-led dosing was associated with higher TTR; leaves open whether algorithm adherence improves outcomes in randomized trials.
Does adherence to a computerised self-adjusting anticoagulant algorithm improve time in the therapeutic range in patients on oral anticoagulants?
Pharmacist-led anticoagulant management achieved better TTR than doctor-led management, largely due to doctors more frequently over-riding the computerised dosing algorithm.
Harper et al. (2014) studied this question.